Does the Future Hold a Botox Lotion?
Revance Therapeutics, a privately held specialty biopharmaceutical company in California, is exploring a Botox product that could be applied to the skin in cream form—no needles necessary, reports WCBS-TV in New York City.
Revance says that it will be two years before clinical trials of the product, called RT001, are complete. Then the FDA will decide whether to approve the drug, which is being tested for use on crow’s feet, according to WCBS-TV.
Some doctors worry about the safety of such a product. In an interview with WCBS-TV, Dr. David Colbert, a New York City dermatologist, says he worries that a Botox lotion product would be so popular that black market versions would be sold online without oversight and that the potential muscle paralyzing effects could be dangerous.
“I think it’s a brilliant idea, but I’m more concerned about the welfare of people who would use it irresponsibly,” he says.
Patients in the early trials tended to see a moderate reduction in wrinkles around their eyes after using the product for a month. The product is being tested on crow’s feet because the skin around the eyes is thin and susceptible to bruising when Botox is injected.
Dr. Richard Glogau, a clinical professor of dermatology at the University of California, San Francisco, who is a primary investigator for the study, said after early trials that Revance needed to rework the formulation so the drug would stay where it was applied and not spread to other parts of the body.
Dr. Anthony Youn, a plastic surgeon in Michigan, had some interesting thoughts on the product’s potential. He writes on his website: “I think a huge application of this topical botulinum toxin is in sweat reduction. Could you imagine an antiperspirant stick with this product that lasts several months with each application and leaves no residue? I’d buy it!”
To watch the WCBS-TV segment, go to http://wcbstv.com/video and search for “Botox cream.” (Pictured: before & after use of RT001 for 28 days; image via WCBS-TV)
Tags: botox
